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Bioengineering

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  Coming 4Q 2009: “Biomedical Optical Diagnostics and Sensing” by Thomas Huser, sponsored by the IEEE Photonics Society

This course provides an introduction to the basics of life sciences, followed by an introduction to the basic properties of photons, and the spectroscopic properties of biological materials, i.e. absorbance, reflectance, polarization, fluorescence and light scattering. Modern optical imaging techniques, based on fluorescence, vibrational and nonlinear concepts and their medical applications will be discussed.

After completing you should be able to develop an understanding of:

  • The basics of life sciences
  • Basic properties of photons
  • Modern optical imaging techniques

Thomas R. Huser is currently an Associate Professor in the Department of Internal Medicine and Chief Scientist for the NSF Center for Biophotonics Science and Technology (CBST) at the University of California at Davis.

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Coming 4Q 2009: “bioMEMS/biosensors and Point-of-care Diagnostics” by Justin Williams, sponsored by the IEEE Engineering in Medicine and Biology Society

This course will provide an introduction to the field of Micro-Electro-Mechanical Systems (MEMS) as it applies to biological applications (BioMEMS).

After completing you should be able to develop an understanding of:

  • an overview of the field of Micro-Electro-Mechanical Systems and how it applies to biological applications

Justin Williams is an Assistant Professor in Biomedical Engineering and Neurological Surgery at the University of Wisconsin.  He received his PhD from Arizona State in Bioengineering and did postdoctoral fellowships in Neuroengineering and Neurosurgery at the University of Michigan and the University of Wisconsin.  His research interests involve BioMEMS device development for neurobiology, neuroscience and neurosurgical applications.  He recently received the IEEE TNSRE 2007 outstanding paper award for his work on microfabricated implants for chronically recording electrical activity from single neurons in the cerebral cortex of behaving animals.

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“Optical Biomedical Sensors” by Claire Gu, sponsored by the IEEE Engineering in Medicine and Biology Society

Early diagnostics of diseases is the key to treatment, cure, and fatality prevention. Various biomedical sensors are available or being developed to achieve early disease diagnostics with non-invasive or minimally invasive techniques, such as magnetic resonance imaging (MRI), ultrasonic imaging, X-ray imaging, CT scan, optical coherent tomography (OCT), endoscopy, microscopy, spectroscopy, etc. Among these techniques, optical technologies, including various microscopy and spectroscopy approaches, provide the possibility to observe a large range of objects, from organs, cells, to molecules, with fast (ideally real-time) response and high spatial and spectral resolutions. In addition, to make the diagnostic tests of diseases, such as cancers, more accessible to the general public it is important to provide easy early diagnostic tools packaged as portable information devices. Such early diagnostics portable information devices must be highly sensitive, disease specific, reliable, inexpensive, easy to fabricate, fast, and compact.

This course will provide an overview of various optical biomedical sensors, including both imaging and spectroscopic techniques, and introduce some recent developments in biomedical sensors, such as nanoparticle surface enhanced Raman scattering (SERS) and its application in compact molecular sensors. Specifically, the following topics will be discussed: interaction of light with tissues, cells, and molecules; bioimaging including optical microscopy, endoscopic imaging, fluorescence imaging, and optical tomography; spectroscopy including absorption spectroscopy, fluorescence spectroscopy, and Raman spectroscopy; optical fiber surface enhanced Raman probes for biomedical applications.

After completing you should be able to develop an understanding of:

  • Various optical biomedical sensors
  • Recent developments in biomedical sensors

Claire Gu received her Ph.D. in Physics from Caltech in 1989. Then she worked as a member of the technical staff at Rockwell Science Center, and went to Penn State in 1992 as an assistant professor. In 1997, she came to UC Santa Cruz as the first Electrical Engineering faculty member, and is now a professor in EE. Her research interests include fiber optics, holographic data storage, liquid crystal displays, nonlinear optics, and optical information processing; with a current emphasis on fiber sensors using SERS (surface enhanced Raman scattering). She has published almost 200 journal and conference papers in these areas. In addition, she has co-authored a text/reference book on "Optics of Liquid Crystal Displays", and co-edited two technical books on photorefractive nonlinear optics and applications.   She received a National Science Foundation Young Investigator Award in 1993.   From 2000 to 2006, she served as a Topical Editor of Optics Letters. In 2007, she has been elected a Fellow of SPIE (The International Society of Optical Engineering).

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“Smart Fabrics and Interactive Textiles: State of Art and Future Challenges” by Rita Paradiso, sponsored by the IEEE Engineering in Medicine and Biology Society

This course will provide a discussion of the use of textile materials for sensing functions. Textile technology for sensors fabrication will be presented. Methods for characterizations will also be discussed and examples of specific applications will be presented. The course will also provide an overview of future developments.

After completing you should be able to develop an understanding of:

  • the use of textile materials for sensing fuctions
  • textile technology for sensors and fabrication
  • Methods for characterizations
  • Potential future developments

Rita Paradiso graduated in Physics from the University of Genoa and received her Ph.D. in Bioengineering in 1991. Molecular Electronics, Biosensors, Biomaterials for biomedical applications have been her main research topics. In particular she worked on functionalisation of surfaces and their characterisation. She worked in London during the Ph.D. at the Physics Department of Queen Mary College.

In 1993 she got a Post Doctor CE fellowship, at the Molecular Chemical Laboratory - CNE Saclay, France. In 1994 she was Post Doctor fellow at the Department of Material Engineering of the University of Trento. During 1998, she worked at the ""IRST-Instituto Trentino di Cultura"" on bio-activation of MEMS, FIBIA.

From 1998-1999 she was Research Manager of Technobiochip s.r.l.- Marciana (LI)-Italy.

She has over 50 scientific publications and conference presentation since 1989.

She joined Smartex in 2000 as R&D Manager, and from September 2001 was the coordinator of WEALTHY (IST-2001-37778), from January 2004, was working in MYHEART an Integrated Project (IST-2002-507816) as coordinator of “Functional Bioclothes” workpackage, she is involved in Biotex (IST-NMP 016789), Proetex (IST-4 026987) and Healthwear ( e-TEN 029402) as e-textile expert.

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